万婵娟   中国科学技术大学，特任副研究员

基本信息

出生年月: 1988年1月

常用邮箱: wancj@ustc.edu.cn

教育与工作经历

2018.10 ~ 至今，中国科学技术大学生命科学与医学部，特任副研究员

2015.07 ~ 2018.09，中国科学院合肥物质科学研究院强磁场中心，博士后

2009.09 ~ 2015.06，中国科学院大学，博士

2005.9-2009.6，南昌大学，学士

论文发表情况

1. Chanjuan Wan, Wenqiang Fu, Haitao Jing, Na Zhang*, NMR study of the novel intermolecular V-shaped G-quadruplex [J]. Nucleic Acids Research. 2019 Feb 20; 47(3):1544-1556.

2. Chanjuan Wan and Chengdong Huang, Solution NMR studies of chaperone-client systems. In Biophysics of Molecular Chaperones: Function, Mechanisms and Client Protein Interactions, ed. S. Hiller, M. Liu, and L. He, Royal Society of Chemistry, 2023, vol. 29, ch. 4, pp. 86-135. Hardback ISBN 978-1-83916-282-4.

3. Chanjuan Wan#, Bo Wu# *, Zhenwei Song , Jiahai Zhang , Huiying Chu, Aoli Wang, Qingsong Liu , Yunyu Shi , Guohui Li, Junfeng Wang*. Insights into the molecular recognition of the granuphilin C2A domain with PI(4,5)P2 [J]. Chemistry and Physics of Lipids, 186(2015) 61-67.

4. Man Wu, Tuo Ji, Chanjuan Wan, Simin Wang*, Chengdong Huang*. Bipartite recognition of tail-anchored proteins by Sgt2 involves both the cytosolic and transmembrane domains. Biochemistry, 2025 Aug 19; 64(16):3549-3558.

5. Tuo Ji, Piao Ge, Shan Zhang, Chanjuan Wan, Hailong Liu, Xiaozhan Qu, Feng Zhu, Qingguo Gong, Weiya Xu, Chao Wang*, Yucai Wang*, & Chengdong Huang*. Distant on-off switching of protein activity by intrinsically disordered region. Nature Structural & Molecular Biology, 2025 Oct; 32(10):2088-2098.

6. Xiaozhan Qu, Shuo Zhao, Chanjuan Wan, Lei Zhu, Paolo Rossi, Junfeng Wang, Charalampos Kalodimos, Chao Wang, Weiya Xu* & Chengdong Huang*, Structural basis for the dynamic chaperoning of disordered clients by Hsp90. Nature Structural & Molecular Biology, 2024 Oct 31(10):1482-1491.

7. Xiaozhan Qu, Simin Wang, Shuo Zhao, Chanjuan Wan, Weiya Xu* and Chengdong Huang*. The dynamic triage interplay of Hsp90 with its chaperone cycle and client binding. Nature Communications, 2024 Dec 11; 15(1):10661.

8. Jinxin Xu#, Leilei Zhang#, Yinghua Ye, Yongli Shan, Chanjuan Wan, Junfeng Wang, Duanqing Pei, Xiaodong Shu, Jingsong Liu*. SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding [J]. Structure. 2017 Aug 1; 25(8):1251-1263.e5.

9. Xiaoshan Shi#, Yunchen Bi#, Wei Yang#, Xingdong Guo, Yan Jiang, Chanjuan Wan, Lunyi Li, Yibing Bai, Jun Guo, Yujuan Wang, Xiangjun Chen, Bo Wu, Hongbin Sun, Wanli Liu, Junfeng Wang* & Chenqi Xu*. Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids [J]. Nature. 2013 Jan 3;493(7430):111-5.

10.Yan Li, Jiarong Wang, Jing Yang, Chanjuan Wan, Xiaoming Wang, Hongbin Sun*. Recombinant expression, purification and characterization of antimicrobial peptide ORBK in Escherichia coli [J]. Protein Expression and Purification, 2014, 95:182-187.