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科研成果

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科研成果

1. Liu R#, Wang T#, Wang C, Xu M, Chen B, Zhao J, Xiong W, Pan S, Ruan Z, Lu N, Zhang Y, Yang G, Meng F, Liu Y, Sun X*, Liu L*. Development and application of G4-Flame as a visual biosensor for G4-DNA. Nucleic Acids Res. 2026, Mar 19;54(6):gkag179.

2. Zhang, Y#; Fu, WQ#; Wang, YH#; Wu, AY; Zhu, ZZ; Yin, XK; Li, Y; Sun, YD; Shi, WP; Cheng, JM; Hu*, LH*; Liu, J*; Cui, J*. Inhibition of DDX5-Mediated G-Quadruplex Unwinding in the beta-Catenin 5'-UTR by Magnesium Isoglycyrrhizinate Alleviates Chemotherapy-Induced Intestinal Injury. Research, 2026, 9 (ja), 1044.

3. Geng Qin, Chuanqi Zhao, Chengming Gao, Wenxuan Hu, Na Zhang, Jinsong Ren, Xiaogang Qu. Nat Commun. 2026, 17(1):3076.

4. Xu, Xiaojuan; Wang, Tao*; Autoregulation of TRF2 through G-Quadruplex-Specific Interaction between the Gene and N-Terminal Domain of the Protein, Biochemistry, 2025, 64(1). 

5. Liu, QQ#; Han, MR#; Wu, ZG#; Fu, WQ#; Ji, J.; Liang, QQ.; Tan, MJ; Zhai, LH; Gao, J; Shi, DQ; Jiang, Q; Sun, ZY; Lai, YP; Xu, Q; Sun, Y. DDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding. Nature Aging, 2024, 4 (5), 664-680.

6. Xucong Teng, Difei Hu, Yicong Dai, Haitao Jing, Wenxuan Hu, Qiushuang Zhang, Na Zhang, Jinghong Li. Angew Chem Int Ed Engl., 2024, 63(38):e202407353.

7. Hu, WX#.; Jing, HT#; Fu, WQ; Wang, ZR; Zhou, J.; Zhang, N*. Conversion to Trimolecular G-Quadruplex by Spontaneous Hoogsteen Pairing-Based Strand Displacement Reaction between Bimolecular G-Quadruplex and Double G-Rich Probes. Journal of the American Chemical Society 2023, 145 (33), 18578-18590.

8. Fu WQ#; Jing, HT#; Xu, XJ.; Xu, SP; Wang, T; Hu, W.; Li, HH; Zhang, N*. Two coexisting pseudo-mirror heteromolecular telomeric G-quadruplexes in opposite loop progressions differentially recognized by a low equivalent of Thioflavin T. Nucleic Acids Research 2021, 49 (18), 10717-10734.

9. Jing HT#, Fu WQ#, Hu WX, Xu SP, Xu XJ, He M, Liu YZ, Zhang N*. NMR structural study on the self-trimerizationof d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Nat solution with a moderate K+ tolerance. Nucleic Acids Research, 2021, 49 (4), 2306-2316.2.

10. Wan CJ, Fu WQ, Jing HT, Zhang N*. NMR solution structure of an asymmetric intermolecular leaped V-shape G-quadruplex: selective recognition of the d(G2NG3NG4) sequence motif by a short linear G-rich DNA probe. NucleicAcids Research. 2019, 47(3), p1544-1556.