中国科学院合肥物质科学研究院强磁场科学中心坐落于安徽省合肥市风景秀丽的科学岛,2008年4月30日经中国科学院批准成立,依托中国科学院合肥物质科学研究院管理(科发人教字〔2008〕133号),其前身是2005年12月20日成立的“合肥强磁场科学技术研究中心”。中心目标:发展强磁... 更多简介 +
稳态强磁场实验装置(Steady High Magnetic Field Facility,简称SHMFF)是国家发改委支持的“十一五”国家重大科技基础设施。SHMFF法人单位是中国科学院合肥物质科学研究院,共建单位是中国科学技术大学。各项任务以中国科学院强磁场科学中心为依托完成... 更多简介 +
题 目:Is LIM kinase really an anticancer target? When the Chemistry takes on the Biology
报告人:Prof. Jonathan Baell
单 位 :Monash Institute of Pharmaceutical Sciences
Monash University
邀请人:刘青松 研究员
时 间: 2012.11.07. (周三)下午 2:00
地 点: 强磁场中心 201 会议室
报告人介绍:Dr Baell, Larkins Fellow and Senior Research Fellow of the National Health and Medical Research Council, is a Professor of Medicinal Chemistry at the Monash Institute of Pharmaceutical Sciences (MIPS, Victoria, Australia), Head of the MIPS-Servier Medicinal Chemistry Program and Head of the Australian Translational Medicinal Chemistry Facility. He is a Fellow of the Royal Australian Chemical Institute.
报告摘要: Over many years, a significant amount of biological evidence has built up that inhibition of LIMK1/2 kinase could result in inhibition of metastatic cancer….and possibly primary tumour growth. As such, the Collaborative Research Centre for Cancer Therapeutics (CTx) initiated a drug discovery program to search for small molecule inhibitors of LIMK1/2 kinase and Professor Baell led this project. This seminar outlines an astonishing outcome with the use of a molecular tool and illustrates the important interplay between chemistry and biology. This short seminar will conclude with a short presentation of some history between China and the speaker’s home Island of Tasmania that not many people know about.
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